3F4B
Crystal structure of Plasmodium berghei Enoyl-acyl-carrier-protein reductase with TRICLOSAN
Summary for 3F4B
Entry DOI | 10.2210/pdb3f4b/pdb |
Related | 1NHG |
Descriptor | Enoyl-acyl carrier protein reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN, ... (4 entities in total) |
Functional Keywords | pbenr, pbfabi, triclosan, oxidoreductase |
Biological source | Plasmodium berghei |
Total number of polymer chains | 4 |
Total formula weight | 147529.21 |
Authors | Sacchettini, J.C.,Tsai, H.-C. (deposition date: 2008-10-31, release date: 2010-03-02, Last modification date: 2023-09-06) |
Primary citation | Yu, M.,Kumar, T.R.,Nkrumah, L.J.,Coppi, A.,Retzlaff, S.,Li, C.D.,Kelly, B.J.,Moura, P.A.,Lakshmanan, V.,Freundlich, J.S.,Valderramos, J.C.,Vilcheze, C.,Siedner, M.,Tsai, J.H.,Falkard, B.,Sidhu, A.B.,Purcell, L.A.,Gratraud, P.,Kremer, L.,Waters, A.P.,Schiehser, G.,Jacobus, D.P.,Janse, C.J.,Ager, A.,Jacobs, W.R.,Sacchettini, J.C.,Heussler, V.,Sinnis, P.,Fidock, D.A. The fatty acid biosynthesis enzyme FabI plays a key role in the development of liver-stage malarial parasites. Cell Host Microbe, 4:567-578, 2008 Cited by PubMed: 19064257DOI: 10.1016/j.chom.2008.11.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)