3F47

The Crystal Structure of [Fe]-Hydrogenase (Hmd) Holoenzyme from Methanocaldococcus jannaschii

3F47 の概要

• エントリーDOI: 10.2210/pdb3f47/pdb
• 関連するPDBエントリー: 2B0J 3DAF 3DAG 3F46
• 分子名称: 5,10-methenyltetrahydromethanopterin hydrogenase, 5'-O-[(S)-hydroxy{[2-hydroxy-3,5-dimethyl-6-(2-oxoethyl)pyridin-4-yl]oxy}phosphoryl]guanosine, FE (II) ION, ... (6 entities in total)
• 機能のキーワード: rossmann fold, helix bundle, complex with iron guanylyl pyridinol cofactor, methanogenesis, one-carbon metabolism, oxidoreductase
• 由来する生物種: Methanocaldococcus jannaschii (Methanococcus jannaschii)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 39400.31

構造登録者

Hiromoto, T.,Pilak, O.,Warkentin, E.,Thauer, R.K.,Shima, S.,Ermler, U. (登録日: 2008-10-31, 公開日: 2009-02-10, 最終更新日: 2023-11-01)

• 主引用文献: Hiromoto, T.,Ataka, K.,Pilak, O.,Vogt, S.,Stagni, M.S.,Meyer-Klaucke, W.,Warkentin, E.,Thauer, R.K.,Shima, S.,Ermler, U.; The crystal structure of C176A mutated [Fe]-hydrogenase suggests an acyl-iron ligation in the active site iron complex.; Febs Lett., 583:585-590, 2009; PubMed: 19162018; DOI: 10.1016/j.febslet.2009.01.017

実験手法

X-RAY DIFFRACTION (1.75 Å)