3EWZ

human orotidyl-5'-monophosphate decarboxylase in complex with 5-cyano-UMP

Summary for 3EWZ
Related3EWU 3EWW 3EWX 3EWY 3EX0 3EX1 3EX2 3EX3 3EX4 3EX5 3EX6
DescriptorOrotidine-5'-phosphate decarboxylase, SULFATE ION, 5-CYANO-URIDINE-5'-MONOPHOSPHATE, ... (4 entities in total)
Functional Keywordsdecarboxylase, tim barrel, unusual catalysis, alternative splicing, disease mutation, glycosyltransferase, lyase, multifunctional enzyme, polymorphism, pyrimidine biosynthesis, transferase
Biological sourceHomo sapiens
Total number of polymer chains4
Total formula weight114787.86
Authors
Heinrich, D.,Diederichsen, U.,Rudolph, M. (deposition date: 2008-10-16, release date: 2009-04-07, Last modification date: 2017-10-25)
Primary citationDiederichsen, U.,Heinrich, D.,Rudolph, M.G.
Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase
Chemistry, 15:6619-6625, 2009
PubMed: 19472232
DOI: 110.1002/chem.200900397
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation
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PDB entries from 2021-06-09