3EQD
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a binary complex with ATP-GS and MG2P
Summary for 3EQD
Entry DOI | 10.2210/pdb3eqd/pdb |
Related | 3EQC 3EQF 3EQG 3EQH 3EQI |
Descriptor | Dual specificity mitogen-activated protein kinase kinase 1, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | mek1 kinase, atp-binding, disease mutation, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 40723.83 |
Authors | Fischmann, T.O. (deposition date: 2008-09-30, release date: 2009-02-24, Last modification date: 2024-02-21) |
Primary citation | Fischmann, T.O.,Smith, C.K.,Mayhood, T.W.,Myers, J.E.,Reichert, P.,Mannarino, A.,Carr, D.,Zhu, H.,Wong, J.,Yang, R.S.,Le, H.V.,Madison, V.S. Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors. Biochemistry, 48:2661-2674, 2009 Cited by PubMed: 19161339DOI: 10.1021/bi801898e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)