3EQI
X-ray structure of the human mitogen-activated protein kinase kinase 1 (MEK1) in a binary complex with ADP and MG2P
Summary for 3EQI
| Entry DOI | 10.2210/pdb3eqi/pdb |
| Related | 3EQC 3EQD 3EQF 3EQG 3EQH |
| Descriptor | Dual specificity mitogen-activated protein kinase kinase 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (6 entities in total) |
| Functional Keywords | mek1 kinase, atp-binding, disease mutation, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, tyrosine-protein kinase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 40627.79 |
| Authors | Fischmann, T.O. (deposition date: 2008-09-30, release date: 2009-02-24, Last modification date: 2024-02-21) |
| Primary citation | Fischmann, T.O.,Smith, C.K.,Mayhood, T.W.,Myers, J.E.,Reichert, P.,Mannarino, A.,Carr, D.,Zhu, H.,Wong, J.,Yang, R.S.,Le, H.V.,Madison, V.S. Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors. Biochemistry, 48:2661-2674, 2009 Cited by PubMed: 19161339DOI: 10.1021/bi801898e PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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