3EOT
Crystal structure of LAC031, an engineered anti-VLA1 Fab
Summary for 3EOT
Entry DOI | 10.2210/pdb3eot/pdb |
Related | 1MHP |
Descriptor | FAB FRAGMENT, HEAVY CHAIN, FAB FRAGMENT, LIGHT CHAIN (3 entities in total) |
Functional Keywords | antibody, fab, vla-1, domain swap, proten engineering, immune system |
Biological source | Mus musculus (mouse) More |
Total number of polymer chains | 2 |
Total formula weight | 47738.90 |
Authors | Boriack-Sjodin, P.A.,Clark, L.A. (deposition date: 2008-09-29, release date: 2009-01-20, Last modification date: 2017-10-25) |
Primary citation | Clark, L.A.,Boriack-Sjodin, P.A.,Day, E.,Eldredge, J.,Fitch, C.,Jarpe, M.,Miller, S.,Li, Y.,Simon, K.,van Vlijmen, H.W. An antibody loop replacement design feasibility study and a loop-swapped dimer structure. Protein Eng.Des.Sel., 22:93-101, 2009 Cited by PubMed: 19074157DOI: 10.1093/protein/gzn072 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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