3ELA
Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor
Summary for 3ELA
Entry DOI | 10.2210/pdb3ela/pdb |
Related PRD ID | PRD_000369 |
Descriptor | Coagulation factor VIIA light chain, Coagulation factor VIIA heavy chain, Tissue factor, ... (8 entities in total) |
Functional Keywords | serine protease, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 69653.77 |
Authors | Bjelke, J.R.,Fodje, M.,Svensson, L.A. (deposition date: 2008-09-21, release date: 2008-11-04, Last modification date: 2023-11-01) |
Primary citation | Bjelke, J.R.,Olsen, O.H.,Fodje, M.,Svensson, L.A.,Bang, S.,Bolt, G.,Kragelund, B.B.,Persson, E. Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity J.Biol.Chem., 283:25863-25870, 2008 Cited by PubMed: 18640965DOI: 10.1074/jbc.M800841200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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