3ELA

Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor

Summary for 3ELA

• Entry DOI: 10.2210/pdb3ela/pdb
• Related PRD ID: PRD_000369
• Descriptor: Coagulation factor VIIA light chain, Coagulation factor VIIA heavy chain, Tissue factor, ... (8 entities in total)
• Functional Keywords: serine protease, blood clotting, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 69653.77

Authors

Bjelke, J.R.,Fodje, M.,Svensson, L.A. (deposition date: 2008-09-21, release date: 2008-11-04, Last modification date: 2023-11-01)

• Primary citation: Bjelke, J.R.,Olsen, O.H.,Fodje, M.,Svensson, L.A.,Bang, S.,Bolt, G.,Kragelund, B.B.,Persson, E.; Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity; J.Biol.Chem., 283:25863-25870, 2008; PubMed: 18640965; DOI: 10.1074/jbc.M800841200

Experimental method

X-RAY DIFFRACTION (2.2 Å)