3EI2
Structure of hsDDB1-drDDB2 bound to a 16 bp abasic site containing DNA-duplex
Summary for 3EI2
Entry DOI | 10.2210/pdb3ei2/pdb |
Related | 3EI1 3EI3 3EI4 |
Descriptor | DNA damage-binding protein 1, DNA damage-binding protein 2, 5'-D(*DAP*DAP*DAP*DTP*DGP*DAP*DAP*DTP*(3DR)P*DAP*DAP*DGP*DCP*DAP*DGP*DG)-3', ... (6 entities in total) |
Functional Keywords | uv-damage, ddb, nucleotide excision repair, xeroderma pigmentosum, alternative splicing, disease mutation, dna damage, dna repair, dna-binding, nucleus, phosphoprotein, polymorphism, wd repeat, ubl conjugation pathway, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (Human) More |
Cellular location | Cytoplasm: Q16531 Nucleus (By similarity): Q2YDS1 |
Total number of polymer chains | 4 |
Total formula weight | 182667.55 |
Authors | Scrima, A.,Thoma, N.H. (deposition date: 2008-09-15, release date: 2009-01-20, Last modification date: 2024-03-20) |
Primary citation | Scrima, A.,Konickova, R.,Czyzewski, B.K.,Kawasaki, Y.,Jeffrey, P.D.,Groisman, R.,Nakatani, Y.,Iwai, S.,Pavletich, N.P.,Thoma, N.H. Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell(Cambridge,Mass.), 135:1213-1223, 2008 Cited by PubMed: 19109893DOI: 10.1016/j.cell.2008.10.045 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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