3EE7

Crystal Structure of SARS-CoV nsp9 G104E

Summary for 3EE7

• Entry DOI: 10.2210/pdb3ee7/pdb
• Related: 1QZ8 1UW7 2J97 2J98
• Descriptor: Replicase polyprotein 1a, PHOSPHATE ION, GLYCEROL, ... (4 entities in total)
• Functional Keywords: gxxxg, dimerization, sars-cov, helix-helix, hydrolase, membrane, metal-binding, protease, rna-binding, thiol protease, transmembrane, zinc-finger, viral protein
• Biological source: SARS coronavirus (SARS-CoV)
• Cellular location: Non-structural protein 3: Host membrane ; Multi-pass membrane protein . Non-structural protein 4: Host membrane ; Multi-pass membrane protein . Non-structural protein 6: Host membrane ; Multi-pass membrane protein . Non-structural protein 7: Host cytoplasm, host perinuclear region . Non-structural protein 8: Host cytoplasm, host perinuclear region . Non-structural protein 9: Host cytoplasm, host perinuclear region . Non-structural protein 10: Host cytoplasm, host perinuclear region : P0C6U8
• Total number of polymer chains: 4
• Total formula weight: 56466.66

Authors

Miknis, Z.J.,Donaldson, E.F.,Umland, T.C.,Rimmer, R.,Baric, R.S.,Schultz, L.W. (deposition date: 2008-09-04, release date: 2009-03-24, Last modification date: 2023-08-30)

• Primary citation: Miknis, Z.J.,Donaldson, E.F.,Umland, T.C.,Rimmer, R.A.,Baric, R.S.,Schultz, L.W.; Severe acute respiratory syndrome coronavirus nsp9 dimerization is essential for efficient viral growth; J.Virol., 83:3007-3018, 2009; PubMed: 19153232; DOI: 10.1128/JVI.01505-08

Experimental method

X-RAY DIFFRACTION (2.6 Å)