3EE2
Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Summary for 3EE2
Entry DOI | 10.2210/pdb3ee2/pdb |
Related | 1IYH 1IYI 1PD2 1V40 2CVD |
Descriptor | Glutathione-requiring prostaglandin D synthase, GLUTATHIONE, nocodazole, ... (5 entities in total) |
Functional Keywords | h-pgds, prostanoid production, inflamation, nocodazole, glutathione transferase sigma, fatty acid biosynthesis, isomerase, lipid synthesis, prostaglandin biosynthesis |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : O60760 |
Total number of polymer chains | 2 |
Total formula weight | 47402.66 |
Authors | Oakley, A.J. (deposition date: 2008-09-04, release date: 2008-09-16, Last modification date: 2023-11-01) |
Primary citation | Weber, J.E.,Oakley, A.J.,Christ, A.N.,Clark, A.G.,Hayes, J.D.,Hall, R.,Hume, D.A.,Board, P.G.,Smythe, M.L.,Flanagan, J.U. Identification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase Eur.J.Med.Chem., 45:447-454, 2010 Cited by PubMed: 19939518DOI: 10.1016/j.ejmech.2009.10.025 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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