3ECS
Crystal structure of human eIF2B alpha
Summary for 3ECS
Entry DOI | 10.2210/pdb3ecs/pdb |
Descriptor | Translation initiation factor eIF-2B subunit alpha, SULFATE ION, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | eukaryotic translation initiation factor 2balpha (eif2balpha), guanine nucleotide exchange factor (gef), translation, initiation, stress response, disease mutation, initiation factor, protein biosynthesis, structural genomics, riken structural genomics/proteomics initiative, rsgi |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 8 |
Total formula weight | 283025.15 |
Authors | Hiyama, T.B.,Ito, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2008-09-01, release date: 2009-09-01, Last modification date: 2014-02-05) |
Primary citation | Hiyama, T.B.,Ito, T.,Imataka, H.,Yokoyama, S. Crystal structure of the alpha subunit of human translation initiation factor 2B J.Mol.Biol., 392:937-951, 2009 Cited by PubMed: 19631657DOI: 10.1016/j.jmb.2009.07.054 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.65 Å) |
Structure validation
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