3ECR

Structure of human porphobilinogen deaminase

3ECR の概要

• エントリーDOI: 10.2210/pdb3ecr/pdb
• 分子名称: Porphobilinogen deaminase, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid (3 entities in total)
• 機能のキーワード: human porphobilinogen deaminase, heme biosynthesis, porphobilinogen hinge, alternative splicing, cytoplasm, disease mutation, porphyrin biosynthesis, transferase
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cytoplasm (Probable): P08397
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 80151.37

構造登録者

Song, G.,Li, Y.,Cheng, C.,Zhao, Y.,Gao, A.,Zhang, R.,Joachimiak, A.,Shaw, N.,Liu, Z.J. (登録日: 2008-09-01, 公開日: 2008-09-30, 最終更新日: 2024-03-20)

• 主引用文献: Song, G.,Li, Y.,Cheng, C.,Zhao, Y.,Gao, A.,Zhang, R.,Joachimiak, A.,Shaw, N.,Liu, Z.J.; Structural insight into acute intermittent porphyria.; Faseb J., 23:396-404, 2009; PubMed: 18936296; DOI: 10.1096/fj.08-115469

実験手法

X-RAY DIFFRACTION (2.182 Å)