3ECB

Crystal structure of mouse H-2Dd in complex with peptide P18-I10 derived from human immunodeficiency virus envelope glycoprotein 120

3ECB の概要

• エントリーDOI: 10.2210/pdb3ecb/pdb
• 関連するPDBエントリー: 3DMM
• 分子名称: H-2 class I histocompatibility antigen, D-D alpha chain, Beta-2 microglobulin, Peptide P18-I10 from HIV gp160, ... (6 entities in total)
• 機能のキーワード: class i major histompatibility complex, mhc-i, h-2dd, glycoprotein, immune response, membrane, mhc i, phosphoprotein, transmembrane, immunoglobulin domain, secreted, aids, apoptosis, cell membrane, cleavage on pair of basic residues, coiled coil, envelope protein, fusion protein, host-virus interaction, lipoprotein, palmitate, viral immunoevasion, virion, immune system
• 由来する生物種: Mus musculus (mouse); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P01900; Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P19551
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45529.43

構造登録者

Natarajan, K.,Wang, R.,Margulies, D.H. (登録日: 2008-08-29, 公開日: 2009-07-14, 最終更新日: 2023-08-30)

• 主引用文献: Wang, R.,Natarajan, K.,Margulies, D.H.; Structural basis of the CD8alphabeta/MHC class i interaction: focused recognition orients CD8beta to a T cell proximal position; J.Immunol., 183:2554-2564, 2009; PubMed: 19625641; DOI: 10.4049/jimmunol.0901276

実験手法

X-RAY DIFFRACTION (1.698 Å)