3EBA
CAbHul6 FGLW mutant (humanized) in complex with human lysozyme
Summary for 3EBA
Entry DOI | 10.2210/pdb3eba/pdb |
Related | 1op9 |
Descriptor | CAbHul6, Lysozyme C, SULFATE ION, ... (4 entities in total) |
Functional Keywords | antigen-antibody complex, immunoglobulin, nanobody, humanization, amyloid fibril formation inhibition, amyloid, antimicrobial, bacteriolytic enzyme, disease mutation, glycosidase, hydrolase, polymorphism, immune system-hydrolase complex, immune system/hydrolase |
Biological source | Camelus dromedarius More |
Cellular location | Secreted: P61626 |
Total number of polymer chains | 2 |
Total formula weight | 29148.28 |
Authors | Loris, R.,Vincke, C.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K. (deposition date: 2008-08-27, release date: 2008-12-02, Last modification date: 2023-11-01) |
Primary citation | Vincke, C.,Loris, R.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K. General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold J.Biol.Chem., 284:3273-3284, 2009 Cited by PubMed: 19010777DOI: 10.1074/jbc.M806889200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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