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3EBA

CAbHul6 FGLW mutant (humanized) in complex with human lysozyme

Functional Information from GO Data
ChainGOidnamespacecontents
B0003796molecular_functionlysozyme activity
B0003824molecular_functioncatalytic activity
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0006954biological_processinflammatory response
B0008152biological_processmetabolic process
B0016787molecular_functionhydrolase activity
B0016798molecular_functionhydrolase activity, acting on glycosyl bonds
B0019730biological_processantimicrobial humoral response
B0031640biological_processkilling of cells of another organism
B0035578cellular_componentazurophil granule lumen
B0035580cellular_componentspecific granule lumen
B0042742biological_processdefense response to bacterium
B0042802molecular_functionidentical protein binding
B0050829biological_processdefense response to Gram-negative bacterium
B0050830biological_processdefense response to Gram-positive bacterium
B0070062cellular_componentextracellular exosome
B1904724cellular_componenttertiary granule lumen
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 128
ChainResidue
AARG35
AASP59
ASER60
AHOH215
AHOH216
BGLN126

site_idAC2
Number of Residues9
DetailsBINDING SITE FOR RESIDUE SO4 A 129
ChainResidue
AASN71
AALA72
AHOH192
AHOH210
AHOH260
AHOH261
AGLN1
AGLN3
AASP70

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 130
ChainResidue
ATYR56
ATRP101
BARG5
BHIS78

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 131
ChainResidue
ATHR55
ATYR57
AHOH241
BARG21

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 A 132
ChainResidue
AVAL12
AGLN13
AGLY16
AGLU43
AHOH148
AHOH251
AHOH252

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 131
ChainResidue
BGLU7
BARG10
BTHR11
BARG14

Functional Information from PROSITE/UniProt
site_idPS00128
Number of Residues19
DetailsGLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC
ChainResidueDetails
BCYS77-CYS95

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE:
ChainResidueDetails
BGLU35
BASP53

218853

PDB entries from 2024-04-24

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