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3EBA

CAbHul6 FGLW mutant (humanized) in complex with human lysozyme

Summary for 3EBA
Entry DOI10.2210/pdb3eba/pdb
Related1op9
DescriptorCAbHul6, Lysozyme C, SULFATE ION, ... (4 entities in total)
Functional Keywordsantigen-antibody complex, immunoglobulin, nanobody, humanization, amyloid fibril formation inhibition, amyloid, antimicrobial, bacteriolytic enzyme, disease mutation, glycosidase, hydrolase, polymorphism, immune system-hydrolase complex, immune system/hydrolase
Biological sourceCamelus dromedarius
More
Cellular locationSecreted: P61626
Total number of polymer chains2
Total formula weight29148.28
Authors
Loris, R.,Vincke, C.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K. (deposition date: 2008-08-27, release date: 2008-12-02, Last modification date: 2023-11-01)
Primary citationVincke, C.,Loris, R.,Saerens, D.,Martinez-Rodriguez, S.,Muyldermans, S.,Conrath, K.
General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
J.Biol.Chem., 284:3273-3284, 2009
Cited by
PubMed: 19010777
DOI: 10.1074/jbc.M806889200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

217705

건을2024-03-27부터공개중

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