3E9S

A new class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication

3E9S の概要

• エントリーDOI: 10.2210/pdb3e9s/pdb
• 関連するPDBエントリー: 2FE8
• 分子名称: Non-structural protein 3, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION, ... (5 entities in total)
• 機能のキーワード: sars, virus, coronavirus, papain, papain-like, protease, plpro, nsp3, cytoplasm, hydrolase, membrane, metal-binding, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• 由来する生物種: SARS coronavirus (SARS-CoV)
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6U8
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 36167.13

構造登録者

Mesecar, A.D.,Ratia, K.,Pegan, S. (登録日: 2008-08-23, 公開日: 2008-10-07, 最終更新日: 2011-07-13)

• 主引用文献: Mesecar, A.D.,Ratia, K.,Pegan, S.; A new class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication; To be published,

実験手法