3E7F

Crystal structure of 6-phosphogluconolactonase from Trypanosoma brucei complexed with 6-phosphogluconic acid

Summary for 3E7F

• Entry DOI: 10.2210/pdb3e7f/pdb
• Related: 2J0E
• Descriptor: 6-phosphogluconolactonase, ZINC ION, 6-PHOSPHOGLUCONIC ACID, ... (4 entities in total)
• Functional Keywords: catalytic mechanism, pentose phosphate pathway, 6-phosphogluconolactonase, trypanosoma brucei, hydrolase, zinc binding site
• Biological source: Trypanosoma brucei
• Total number of polymer chains: 2
• Total formula weight: 57780.47

Authors

Poggi, L.,Delarue, M.,Duclert-Savatier, N.,Stoven, V. (deposition date: 2008-08-18, release date: 2009-05-26, Last modification date: 2024-02-21)

• Primary citation: Duclert-Savatier, N.,Poggi, L.,Miclet, E.,Lopes, P.,Ouazzani, J.,Chevalier, N.,Nilges, M.,Delarue, M.,Stoven, V.; Insights into the enzymatic mechanism of 6-phosphogluconolactonase from Trypanosoma brucei using structural data and molecular dynamics simulation.; J.Mol.Biol., 388:1009-1021, 2009; PubMed: 19345229; DOI: 10.1016/j.jmb.2009.03.063

Experimental method

X-RAY DIFFRACTION (2.2 Å)