3E0L
Computationally Designed Ammelide Deaminase
Summary for 3E0L
| Entry DOI | 10.2210/pdb3e0l/pdb |
| Related | 2UZ9 |
| Descriptor | Guanine deaminase, ZINC ION (3 entities in total) |
| Functional Keywords | computational-design backbone-flexibility loop-remodeling guanine cytosine ammelide deaminase, hydrolase, metal-binding, zinc |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 102084.02 |
| Authors | Murphy, P.M.,Bolduc, J.M.,Gallaher, J.L.,Stoddard, B.L.,Baker, D. (deposition date: 2008-07-31, release date: 2009-03-03, Last modification date: 2023-08-30) |
| Primary citation | Murphy, P.M.,Bolduc, J.M.,Gallaher, J.L.,Stoddard, B.L.,Baker, D. Alteration of enzyme specificity by computational loop remodeling and design. Proc.Natl.Acad.Sci.USA, 106:9215-9220, 2009 Cited by PubMed: 19470646DOI: 10.1073/pnas.0811070106 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.37 Å) |
Structure validation
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