3E0L

Computationally Designed Ammelide Deaminase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0006139	biological_process	nucleobase-containing compound metabolic process
A	0006147	biological_process	guanine catabolic process
A	0006161	biological_process	deoxyguanosine catabolic process
A	0007399	biological_process	nervous system development
A	0008270	molecular_function	zinc ion binding
A	0008892	molecular_function	guanine deaminase activity
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0046038	biological_process	GMP catabolic process
A	0046055	biological_process	dGMP catabolic process
A	0046098	biological_process	guanine metabolic process
A	0046872	molecular_function	metal ion binding
B	0005829	cellular_component	cytosol
B	0006139	biological_process	nucleobase-containing compound metabolic process
B	0006147	biological_process	guanine catabolic process
B	0006161	biological_process	deoxyguanosine catabolic process
B	0007399	biological_process	nervous system development
B	0008270	molecular_function	zinc ion binding
B	0008892	molecular_function	guanine deaminase activity
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0046038	biological_process	GMP catabolic process
B	0046055	biological_process	dGMP catabolic process
B	0046098	biological_process	guanine metabolic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 1452

Chain	Residue
A	HIS82
A	HIS84
A	HIS238
A	ASP328
A	HOH1463

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 1452

Chain	Residue
B	HOH1468
B	HIS82
B	HIS84
B	HIS238
B	ASP328

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22662200","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2UZ9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22662200","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2UZ9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---