3E0G

Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5

Summary for 3E0G

Entry DOI	10.2210/pdb3e0g/pdb
Descriptor	Leukemia inhibitory factor receptor, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
Functional Keywords	ig domain, cytokine binding homology region (chr), cell membrane, disease mutation, glycoprotein, membrane, receptor, secreted, transmembrane, signaling protein-cytokine complex, signaling protein/cytokine
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	57067.00
Authors	Lupardus, P.J.,Garcia, K.C. (deposition date: 2008-07-31, release date: 2008-09-23, Last modification date: 2021-10-20)
Primary citation	Skiniotis, G.,Lupardus, P.J.,Martick, M.,Walz, T.,Garcia, K.C. Structural organization of a full-length gp130/LIF-R cytokine receptor transmembrane complex. Mol.Cell, 31:737-748, 2008 Cited by PubMed: 18775332 DOI: 10.1016/j.molcel.2008.08.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation