3E0G
Structure of the Leukemia Inhibitory Factor Receptor (LIF-R) domains D1-D5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Leukemia inhibitory factor receptor | polymer | 483 | 54915.0 | 1 | UniProt (P42702) Pfam (PF18207) Pfam (PF17971) Pfam (PF21177) Pfam (PF00041) In PDB | Homo sapiens (Human) | LIF receptor, LIF-R |
| 2 | B | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 732.7 | 1 | In PDB GlyTouCan (G47477HI) | |||
| 3 | C, E | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) |
Sequence modifications
A: 1 - 483 (UniProt: P42702)
| PDB | External Database | Details |
|---|---|---|
| Gln 13 | Asn 64 | engineered mutation |
| Gln 34 | Asn 85 | engineered mutation |
| Gln 92 | Asn 143 | engineered mutation |
| Gln 140 | Asn 191 | engineered mutation |
| Gln 192 | Asn 243 | engineered mutation |
| Gln 434 | Lys 485 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54915.0 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 2152.0 | |
| All* | Total formula weight | 57067.0 |
