3DY6

PPARdelta complexed with an anthranilic acid partial agonist

Summary for 3DY6

Entry DOI	10.2210/pdb3dy6/pdb
Related	1gwx
Descriptor	Peroxisome proliferator-activated receptor delta, IODIDE ION, 2-({[3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)phenyl]carbonyl}amino)benzoic acid, ... (4 entities in total)
Functional Keywords	ppar, nulear receptor, activator, dna-binding, metal-binding, nucleus, transcription, transcription regulation, zinc-finger
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q03181
Total number of polymer chains	2
Total formula weight	63033.99
Authors	Lambert, M.L.,Xu, R.,Shearer, B.G.,Wilson, T.M. (deposition date: 2008-07-25, release date: 2008-10-07, Last modification date: 2023-08-30)
Primary citation	Shearer, B.G.,Patel, H.S.,Billin, A.N.,Way, J.M.,Winegar, D.A.,Lambert, M.H.,Xu, R.X.,Leesnitzer, L.M.,Merrihew, R.V.,Huet, S.,Willson, T.M. Discovery of a novel class of PPARdelta partial agonists Bioorg.Med.Chem.Lett., 18:5018-5022, 2008 Cited by PubMed: 18722772 DOI: 10.1016/j.bmcl.2008.08.011 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation