1GWX

MOLECULAR RECOGNITION OF FATTY ACIDS BY PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS

Summary for 1GWX

Entry DOI	10.2210/pdb1gwx/pdb
Descriptor	PROTEIN (PPAR-DELTA), 2-(4-{3-[1-[2-(2-CHLORO-6-FLUORO-PHENYL)-ETHYL]-3-(2,3-DICHLORO-PHENYL)-UREIDO]-PROPYL}-PHENOXY)-2-METHYL-PROPIONIC ACID (3 entities in total)
Functional Keywords	ppar, fatty acids, transcription, nuclear receptor fold
Biological source	Homo sapiens (human)
Cellular location	Nucleus: Q03181
Total number of polymer chains	2
Total formula weight	63197.90
Authors	Xu, H.E.,Lambert, M.H.,Montana, V.G.,Park, D.J.,Blanchard, S.,Brown, P.,Sternbach, D.,Lehmann, J.,Bruce, G.W.,Willson, T.M.,Kliewer, S.A.,Milburn, M.V. (deposition date: 1999-03-17, release date: 2000-03-17, Last modification date: 2023-12-27)
Primary citation	Xu, H.E.,Lambert, M.H.,Montana, V.G.,Parks, D.J.,Blanchard, S.G.,Brown, P.J.,Sternbach, D.D.,Lehmann, J.M.,Wisely, G.B.,Willson, T.M.,Kliewer, S.A.,Milburn, M.V. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. Mol.Cell, 3:397-403, 1999 Cited by PubMed: 10198642 DOI: 10.1016/S1097-2765(00)80467-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation