3DY4
Crystal structure of yeast 20S proteasome in complex with spirolactacystin
Summary for 3DY4
Entry DOI | 10.2210/pdb3dy4/pdb |
Related | 1RYP 3DY3 |
Descriptor | Proteasome component Y7, Proteasome component C11, Proteasome component PRE2, ... (16 entities in total) |
Functional Keywords | proteasome, inhibitor, protein degradation, ubiquitin-proteasome-pathway, hydrolase, nucleus, protease, threonine protease, phosphoprotein, zymogen |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Cellular location | Cytoplasm: P23639 P22141 P30656 P23724 P30657 P38624 P23638 P40303 P32379 P40302 P21242 P21243 P25043 P25451 |
Total number of polymer chains | 28 |
Total formula weight | 705067.22 |
Authors | Groll, M.,Balskus, E.,Jacobsen, E. (deposition date: 2008-07-25, release date: 2008-11-04, Last modification date: 2024-03-13) |
Primary citation | Groll, M.,Balskus, E.P.,Jacobsen, E.N. Structural analysis of spiro beta-lactone proteasome inhibitors. J.Am.Chem.Soc., 130:14981-14983, 2008 Cited by PubMed: 18928262DOI: 10.1021/ja806059t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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