3DT0

Understanding Thrombin Inhibition

Summary for 3DT0

• Entry DOI: 10.2210/pdb3dt0/pdb
• Related: 2ZC9 2ZDA 2ZFP 2ZGX 2ZHQ 2ZNK
• Related PRD ID: PRD_000590
• Descriptor: Thrombin light chain, Thrombin heavy chain, Hirudin variant-1, ... (6 entities in total)
• Functional Keywords: blood clotting, hydrolase inhibitor, acute phase, blood coagulation, gamma-carboxyglutamic acid, glycoprotein, hydrolase, kringle, protease, secreted, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35680.04

Authors

Baum, B.,Heine, A.,Klebe, G. (deposition date: 2008-07-14, release date: 2009-06-23, Last modification date: 2023-11-15)

• Primary citation: Baum, B.,Hangauer, D.,Heine, A.,Klebe, G.; Understanding Thrombin Inhibition; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)