3DS1
HIV-1 capsid C-terminal domain mutant (E187A) in complex with an inhibitor of particle assembly (CAI)
Summary for 3DS1
Entry DOI | 10.2210/pdb3ds1/pdb |
Related | 3DPH 3DS0 3DS2 3DS3 3DS4 3DS5 3DTJ |
Descriptor | HIV-1 CAPSID PROTEIN, Peptide Inhibitor of capsid assembly (3 entities in total) |
Functional Keywords | hiv, capsid, mutant, inhibitor, assembly, polyprotein, complex (viral protein-peptide), mainly alpha, viral protein |
Biological source | Human immunodeficiency virus 1 (HIV-1) More |
Total number of polymer chains | 2 |
Total formula weight | 10918.45 |
Authors | Vaney, M.-C.,Igonet, S.,Rey, F.A. (deposition date: 2008-07-11, release date: 2008-09-02, Last modification date: 2023-08-30) |
Primary citation | Bartonova, V.,Igonet, S.,Sticht, J.,Glass, B.,Habermann, A.,Vaney, M.C.,Sehr, P.,Lewis, J.,Rey, F.A.,Krausslich, H.G. Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283:32024-32033, 2008 Cited by PubMed: 18772135DOI: 10.1074/jbc.M804230200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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