3DS3

HIV-1 capsid C-terminal domain mutant (Y169A) in complex with an inhibitor of particle assembly (CAI)

Summary for 3DS3

Entry DOI	10.2210/pdb3ds3/pdb
Related	3DPH 3DS0 3DS1 3DS2 3DS4 3DS5 3DTJ
Descriptor	HIV-1 CAPSID PROTEIN, Peptide inhibitor of capsid assembly (3 entities in total)
Functional Keywords	hiv, capsid, mutant, inhibitor, assembly, polyprotein, complex (viral protein-peptide), mainly alpha, viral protein
Biological source	Human immunodeficiency virus 1 (HIV-1) More
Total number of polymer chains	4
Total formula weight	21768.79
Authors	Igonet, S.,Vaney, M.C.,Rey, F.A. (deposition date: 2008-07-11, release date: 2008-09-02, Last modification date: 2023-08-30)
Primary citation	Bartonova, V.,Igonet, S.,Sticht, J.,Glass, B.,Habermann, A.,Vaney, M.C.,Sehr, P.,Lewis, J.,Rey, F.A.,Krausslich, H.G. Residues in the HIV-1 Capsid Assembly Inhibitor Binding Site Are Essential for Maintaining the Assembly-competent Quaternary Structure of the Capsid Protein. J.Biol.Chem., 283:32024-32033, 2008 Cited by PubMed: 18772135 DOI: 10.1074/jbc.M804230200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation