3DRA

Candida albicans protein geranylgeranyltransferase-I complexed with GGPP

Summary for 3DRA

• Entry DOI: 10.2210/pdb3dra/pdb
• Related: 1N4P
• Descriptor: Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha, Geranylgeranyltransferase type I beta subunit, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (6 entities in total)
• Functional Keywords: geranylgeranyltrasferase, geranylgeranyltransferase type-i, ggtase, ggtase-i, pggt, prenyltransferase, farnesyltransferase, prenylation, geranylgeranylpyrophosphate, ggpp, geranylgeranyl diphosphate, candida, candida albicans, transferase
• Biological source: Candida albicans (Yeast); More
• Total number of polymer chains: 2
• Total formula weight: 83122.77

Authors

Hast, M.A.,Beese, L.S. (deposition date: 2008-07-10, release date: 2008-09-30, Last modification date: 2024-02-21)

• Primary citation: Hast, M.A.,Beese, L.S.; Structure of protein geranylgeranyltransferase-I from the human pathogen Candida albicans complexed with a lipid substrate.; J.Biol.Chem., 283:31933-31940, 2008; PubMed: 18713740; DOI: 10.1074/jbc.M805330200

Experimental method

X-RAY DIFFRACTION (1.8 Å)