3DRA
Candida albicans protein geranylgeranyltransferase-I complexed with GGPP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004659 | molecular_function | prenyltransferase activity |
| A | 0004660 | molecular_function | protein farnesyltransferase activity |
| A | 0004661 | molecular_function | protein geranylgeranyltransferase activity |
| A | 0004662 | molecular_function | CAAX-protein geranylgeranyltransferase activity |
| A | 0005575 | cellular_component | cellular_component |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005953 | cellular_component | CAAX-protein geranylgeranyltransferase complex |
| A | 0005965 | cellular_component | protein farnesyltransferase complex |
| A | 0007323 | biological_process | peptide pheromone maturation |
| A | 0008318 | molecular_function | protein prenyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0018342 | biological_process | protein prenylation |
| A | 0018343 | biological_process | protein farnesylation |
| A | 0018344 | biological_process | protein geranylgeranylation |
| A | 0051604 | biological_process | protein maturation |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004661 | molecular_function | protein geranylgeranyltransferase activity |
| B | 0005953 | cellular_component | CAAX-protein geranylgeranyltransferase complex |
| B | 0008318 | molecular_function | protein prenyltransferase activity |
| B | 0018344 | biological_process | protein geranylgeranylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 391 |
| Chain | Residue |
| B | ASP294 |
| B | CYS296 |
| B | HIS349 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GRG B 1721 |
| Chain | Residue |
| B | TYR297 |
| B | ARG339 |
| B | TYR163 |
| B | HIS219 |
| B | GLY221 |
| B | CYS225 |
| B | ARG288 |
| B | LYS291 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE B3P A 307 |
| Chain | Residue |
| A | ASP29 |
| A | ASP31 |
| A | TYR32 |
| A | ASN61 |
| A | GLU62 |
| A | ASN99 |
| A | ASP125 |
| A | TYR127 |
| A | LYS164 |
| B | GLN25 |
| B | SER26 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"PFTA 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"PFTA 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"PFTA 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"PFTA 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 34 |
| Details | Repeat: {"description":"PFTA 5"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1d8d |
| Chain | Residue | Details |
| B | TYR297 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1d8d |
| Chain | Residue | Details |
| A | LYS101 |
