3DPL
Structural Insights into NEDD8 Activation of Cullin-RING Ligases: Conformational Control of Conjugation.
Summary for 3DPL
Entry DOI | 10.2210/pdb3dpl/pdb |
Descriptor | Cullin-5, RING-box protein 1, ZINC ION, ... (4 entities in total) |
Functional Keywords | ubiquitin, nedd8, cullin, host-virus interaction, receptor, ubl conjugation, ubl conjugation pathway, acetylation, cytoplasm, dna damage, dna repair, metal-binding, nucleus, zinc, zinc-finger, ligase |
Biological source | Homo sapiens More |
Cellular location | Cytoplasm: P62877 |
Total number of polymer chains | 2 |
Total formula weight | 57278.10 |
Authors | Duda, D.M.,Schulman, B.A. (deposition date: 2008-07-08, release date: 2008-09-30, Last modification date: 2021-10-20) |
Primary citation | Duda, D.M.,Borg, L.A.,Scott, D.C.,Hunt, H.W.,Hammel, M.,Schulman, B.A. Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell(Cambridge,Mass.), 134:995-1006, 2008 Cited by PubMed: 18805092DOI: 10.1016/j.cell.2008.07.022 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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