3DLS

Crystal structure of human PAS kinase bound to ADP

Summary for 3DLS

Entry DOI	10.2210/pdb3dls/pdb
Descriptor	PAS domain-containing serine/threonine-protein kinase, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	pas kinase, pask, protein kinase, drug discovery, atp-binding, kinase, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, transferase, structural genomics, psi-2, protein structure initiative, new york sgx research center for structural genomics, nysgxrc
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	230276.62
Authors	Antonysamy, S.,Bonanno, J.B.,Romero, R.,Russell, M.,Iizuka, M.,Gheyi, T.,Wasserman, S.R.,Rutter, J.,Sauder, J.M.,Burley, S.K.,New York SGX Research Center for Structural Genomics (NYSGXRC) (deposition date: 2008-06-29, release date: 2008-08-26, Last modification date: 2024-02-21)
Primary citation	Kikani, C.K.,Antonysamy, S.A.,Bonanno, J.B.,Romero, R.,Zhang, F.F.,Russell, M.,Gheyi, T.,Iizuka, M.,Emtage, S.,Sauder, J.M.,Turk, B.E.,Burley, S.K.,Rutter, J. Structural bases of PAS domain-regulated kinase (PASK) activation in the absence of activation loop phosphorylation. J.Biol.Chem., 285:41034-41043, 2010 Cited by PubMed: 20943661 DOI: 10.1074/jbc.M110.157594 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation