3DFL
Crystal structure of human Prostasin complexed to 4-guanidinobenzoic acid
Summary for 3DFL
Entry DOI | 10.2210/pdb3dfl/pdb |
Related | 3DFJ |
Descriptor | Prostasin, 4-carbamimidamidobenzoic acid (3 entities in total) |
Functional Keywords | prostasin, serine protease, glycoprotein, hydrolase, membrane, secreted, transmembrane, zymogen |
Biological source | Homo sapiens |
Cellular location | Prostasin: Cell membrane; Single-pass membrane protein. Prostasin light chain: Secreted, extracellular space. Prostasin heavy chain: Secreted, extracellular space: Q16651 |
Total number of polymer chains | 1 |
Total formula weight | 28567.92 |
Authors | Su, H.P.,Rickert, K.W.,Darke, P.L.,Munshi, S.K. (deposition date: 2008-06-12, release date: 2008-10-14, Last modification date: 2021-10-20) |
Primary citation | Rickert, K.W.,Kelley, P.,Byrne, N.J.,Diehl, R.E.,Hall, D.L.,Montalvo, A.M.,Reid, J.C.,Shipman, J.M.,Thomas, B.W.,Munshi, S.K.,Darke, P.L.,Su, H.P. Structure of human prostasin, a target for the regulation of hypertension. J.Biol.Chem., 283:34864-34872, 2008 Cited by PubMed: 18922802DOI: 10.1074/jbc.M805262200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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