3DFJ

Crystal structure of human Prostasin

Summary for 3DFJ

• Entry DOI: 10.2210/pdb3dfj/pdb
• Related: 3DFL
• Descriptor: Prostasin, CHLORIDE ION (3 entities in total)
• Functional Keywords: prostasin, serine protease, glycoprotein, hydrolase, membrane, secreted, transmembrane, zymogen
• Biological source: Homo sapiens
• Cellular location: Prostasin: Cell membrane; Single-pass membrane protein. Prostasin light chain: Secreted, extracellular space. Prostasin heavy chain: Secreted, extracellular space: Q16651
• Total number of polymer chains: 1
• Total formula weight: 28459.65

Authors

Su, H.P.,Rickert, K.W.,Darke, P.L.,Munshi, S.K. (deposition date: 2008-06-12, release date: 2008-10-14, Last modification date: 2021-10-20)

• Primary citation: Rickert, K.W.,Kelley, P.,Byrne, N.J.,Diehl, R.E.,Hall, D.L.,Montalvo, A.M.,Reid, J.C.,Shipman, J.M.,Thomas, B.W.,Munshi, S.K.,Darke, P.L.,Su, H.P.; Structure of human prostasin, a target for the regulation of hypertension.; J.Biol.Chem., 283:34864-34872, 2008; PubMed: 18922802; DOI: 10.1074/jbc.M805262200

Experimental method

X-RAY DIFFRACTION (1.45 Å)