3DFL

Crystal structure of human Prostasin complexed to 4-guanidinobenzoic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Prostasin	polymer	263	28388.7	1	UniProt (Q16651) Pfam (PF00089)	Homo sapiens	Serine protease 8
2	B (A)	4-carbamimidamidobenzoic acid	non-polymer		179.2	1	Chemie (GBS)
3	C (A)	water	water		18.0	270	Chemie (HOH)

Sequence modifications

A: 45 - 289 (UniProt: Q16651)

PDB	External Database	Details
Ser 154	Cys 154	engineered mutation
Ala 203	Cys 203	engineered mutation
Leu 290	-	expression tag
Val 291	-	expression tag
Pro 292	-	expression tag
Arg 293	-	expression tag
Gly 294	-	expression tag
Ser 295	-	expression tag
Gly 296	-	expression tag
Ser 297	-	expression tag
Gly 298	-	expression tag
Ser 299	-	expression tag
Leu 300	-	expression tag
Glu 301	-	expression tag
His 302	-	expression tag
His 303	-	expression tag
His 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	28388.7
Non-Polymers*	Number of molecules	1
	Total formula weight	179.2
All*	Total formula weight	28567.9

*Water molecules are not included.