3DD2

Crystal structure of an RNA aptamer bound to human thrombin

Summary for 3DD2

• Entry DOI: 10.2210/pdb3dd2/pdb
• Related PRD ID: PRD_000020
• Descriptor: Thrombin light chain, Thrombin heavy chain, RNA (26-MER), ... (9 entities in total)
• Functional Keywords: thrombin, aptamer, rna, dna, heparin, exosite, protease, serine protease, hydrolase-hydrolase inhibitor-rna complex, hydrolase/hydrolase inhibitor/rna
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 3
• Total formula weight: 42973.57

Authors

Long, S.B.,Sullenger, B.A. (deposition date: 2008-06-04, release date: 2008-11-11, Last modification date: 2023-08-30)

• Primary citation: Long, S.B.,Long, M.B.,White, R.R.,Sullenger, B.A.; Crystal structure of an RNA aptamer bound to thrombin.; Rna, 14:2504-2512, 2008; PubMed: 18971322; DOI: 10.1261/rna.1239308

Experimental method

X-RAY DIFFRACTION (1.9 Å)