3D8Y

RNase A- 5'-Deoxy-5'-N-piperidinothymidine complex

Summary for 3D8Y

Entry DOI	10.2210/pdb3d8y/pdb
Related	3D8Z
Descriptor	Ribonuclease pancreatic, CITRATE ANION, 5'-deoxy-5'-piperidin-1-ylthymidine, ... (4 entities in total)
Functional Keywords	ribonuclease, hydrolase, ligand binding, endonuclease, glycation, glycoprotein, nuclease, secreted
Biological source	Bos taurus (Bovine)
Cellular location	Secreted: P61823
Total number of polymer chains	2
Total formula weight	28104.21
Authors	Leonidas, D.D.,Zographos, S.E.,Oikonomakos, N.G. (deposition date: 2008-05-26, release date: 2009-02-10, Last modification date: 2023-11-01)
Primary citation	Samanta, A.,Leonidas, D.D.,Dasgupta, S.,Pathak, T.,Zographos, S.E.,Oikonomakos, N.G. Morpholino, piperidino, and pyrrolidino derivatives of pyrimidine nucleosides as inhibitors of ribonuclease A: synthesis, biochemical, and crystallographic evaluation J.Med.Chem., 52:932-942, 2009 Cited by PubMed: 19173562 DOI: 10.1021/jm800724t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.72 Å)

Structure validation