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3D70

Crystal structure of E253A mutant of BMRR bound to 22-bp oligonucleotide

Summary for 3D70
Entry DOI10.2210/pdb3d70/pdb
Related1BOW 1EXJ 1R8E 2BOW 3D6Y 3D6Z 3D71
DescriptorBMR promoter DNA, Multidrug-efflux transporter 1 regulator, IMIDAZOLE, ... (5 entities in total)
Functional Keywordsmultidrug resistance, transcription regulation, protein-dna complex, activator, dna-binding, transcription regulator-dna complex, transcription regulator/dna
Biological sourceBacillus subtilis
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Total number of polymer chains2
Total formula weight41473.69
Authors
Newberry, K.J.,Brennan, R.G. (deposition date: 2008-05-20, release date: 2008-08-26, Last modification date: 2023-08-30)
Primary citationNewberry, K.J.,Huffman, J.L.,Miller, M.C.,Vazquez-Laslop, N.,Neyfakh, A.A.,Brennan, R.G.
Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket and Transcription Activation through Tyrosine Expulsion
J.Biol.Chem., 283:26795-26804, 2008
Cited by
PubMed: 18658145
DOI: 10.1074/jbc.M804191200
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

数据于2024-03-27公开中

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