3D6G
Fc fragment of IgG1 (Herceptin) with protein-A mimetic peptide dendrimer ligand.
Summary for 3D6G
Entry DOI | 10.2210/pdb3d6g/pdb |
Related | 1HZH 1L6X 2DTQ |
Descriptor | Ig gamma-1 chain C region, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-[[(2S)-2,6-bis[[(2S)-2,6-bis[[(2R)-2-[[(2R,3R)-2-[[(2R)-2-amino-5-carbamimidamido-pentanoyl]amino]-3-hydroxy-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]hexanoyl]amino]ethanoic acid, ... (4 entities in total) |
Functional Keywords | fc fragment, igg1, glycosilated protein, protein a mimetic peptide dendrimer ligand, glycoprotein, immunoglobulin c region, immunoglobulin domain, secreted, immune system |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 52645.82 |
Authors | Bujacz, A.D.,Redzynia, I.,Bujacz, G.D.,Dinon, F.,Pengo, P.,Fassina, G. (deposition date: 2008-05-19, release date: 2009-06-16, Last modification date: 2023-11-01) |
Primary citation | Moiani, D.,Salvalaglio, M.,Cavallotti, C.,Bujacz, A.,Redzynia, I.,Bujacz, G.,Dinon, F.,Pengo, P.,Fassina, G. Structural characterization of a Protein A mimetic peptide dendrimer bound to human IgG. J.Phys.Chem.B, 113:16268-16275, 2009 Cited by PubMed: 19924842DOI: 10.1021/jp909405b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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