3D6G

Fc fragment of IgG1 (Herceptin) with protein-A mimetic peptide dendrimer ligand.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ig gamma-1 chain C region	polymer	210	23788.8	2	UniProt (P01857) Pfam (PF07654)	Homo sapiens (Human)
2	C, D (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	2	In PDB GlyTouCan (G80858MF)
3	E (B)	2-[[(2S)-2,6-bis[[(2S)-2,6-bis[[(2R)-2-[[(2R,3R)-2-[[(2R)-2-amino-5-carbamimidamido-pentanoyl]amino]-3-hydroxy-butanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoyl]amino]hexanoyl]amino]ethanoic acid	non-polymer		2141.4	1	Chemie (X12)
4	F, G (A, B)	water	water		18.0	268	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47577.7
Branched	Number of molecules	2
	Total formula weight	2926.7
Non-Polymers*	Number of molecules	1
	Total formula weight	2141.4
All*	Total formula weight	52645.8

*Water molecules are not included.