Crystal structure of a phosphorylated Polo-like kinase 1 (Plk1) catalytic domain in complex with ADP.

Summary for 3D5W

Related3d5u 3d5v 3d5x
DescriptorPolo-like kinase 1, ADENOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordspolo-like kinase 1, plk1, catalytic domain, small-molecule inhibitor, kinase, transferase
Biological sourceDanio rerio (leopard danio,zebra danio,zebra fish)
Total number of polymer chains1
Total molecular weight36486.15
Elling, R.A.,Fucini, R.V.,Romanowski, M.J. (deposition date: 2008-05-17, release date: 2008-08-26, Last modification date: 2011-07-13)
Primary citation
Elling, R.A.,Fucini, R.V.,Romanowski, M.J.
Structures of the wild-type and activated catalytic domains of Brachydanio rerio Polo-like kinase 1 (Plk1): changes in the active-site conformation and interactions with ligands.
Acta Crystallogr.,Sect.D, 64:909-918, 2008
PubMed: 18703838 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444908019513
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25540.7%2.5%3.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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