3D5V
Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain.
Summary for 3D5V
| Entry DOI | 10.2210/pdb3d5v/pdb |
| Related | 3d5u 3d5w 3d5x |
| Descriptor | Polo-like kinase 1 (2 entities in total) |
| Functional Keywords | polo-like kinase 1, plk1, catalytic domain, small-molecule inhibitor, kinase, transferase |
| Biological source | Danio rerio (leopard danio,zebra danio,zebra fish) |
| Total number of polymer chains | 1 |
| Total formula weight | 35992.95 |
| Authors | Elling, R.A.,Fucini, R.V.,Romanowski, M.J. (deposition date: 2008-05-17, release date: 2008-08-26, Last modification date: 2023-08-30) |
| Primary citation | Elling, R.A.,Fucini, R.V.,Romanowski, M.J. Structures of the wild-type and activated catalytic domains of Brachydanio rerio Polo-like kinase 1 (Plk1): changes in the active-site conformation and interactions with ligands. Acta Crystallogr.,Sect.D, 64:909-918, 2008 Cited by PubMed: 18703838DOI: 10.1107/S0907444908019513 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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