3D4S
Cholesterol bound form of human beta2 adrenergic receptor.
Summary for 3D4S
Entry DOI | 10.2210/pdb3d4s/pdb |
Related | 2RH1 |
Descriptor | Beta-2 adrenergic receptor/T4-lysozyme chimera, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, CHOLESTEROL, ... (5 entities in total) |
Functional Keywords | gpcr, membrane protein, lysozyme, fusion, adrenergic, timolol, g-protein coupled receptor, glycoprotein, lipoprotein, palmitate, phosphoprotein, receptor, transducer, transmembrane, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d, gpcr network |
Biological source | Homo sapiens More |
Cellular location | Cell membrane ; Multi- pass membrane protein : P07550 |
Total number of polymer chains | 1 |
Total formula weight | 58117.27 |
Authors | Hanson, M.A.,Cherezov, V.,Roth, C.B.,Griffith, M.T.,Jaakola, V.-P.,Chien, E.Y.T.,Velasquez, J.,Kuhn, P.,Stevens, R.C.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D),GPCR Network (GPCR) (deposition date: 2008-05-14, release date: 2008-06-17, Last modification date: 2023-08-30) |
Primary citation | Hanson, M.A.,Cherezov, V.,Griffith, M.T.,Roth, C.B.,Jaakola, V.P.,Chien, E.Y.,Velasquez, J.,Kuhn, P.,Stevens, R.C. A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Structure, 16:897-905, 2008 Cited by PubMed: 18547522DOI: 10.1016/j.str.2008.05.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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