3D3L
The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type
Summary for 3D3L
Entry DOI | 10.2210/pdb3d3l/pdb |
Descriptor | Arachidonate 12-lipoxygenase, 12S-type, FE (III) ION (3 entities in total) |
Functional Keywords | alox12, iron-binding protein, arachidonate 12-lipoxygenase, 12-lox, platelet-type lipoxygenase 12, oxygenase, arachidonate, structural genomics, structural genomics consortium, sgc, cytoplasm, dioxygenase, leukotriene biosynthesis, metal-binding, oxidoreductase, polymorphism |
Biological source | Homo sapiens |
Cellular location | Cytoplasm: P18054 |
Total number of polymer chains | 2 |
Total formula weight | 122431.95 |
Authors | Tresaugues, L.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Olesen, K.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Welin, M.,Weigelt, J.,Wikstrom, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (deposition date: 2008-05-12, release date: 2008-09-09, Last modification date: 2023-08-30) |
Primary citation | Tresaugues, L.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Olesen, K.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Welin, M.,Weigelt, J.,Wikstrom, M.,Nordlund, P. Crystal structure of the lipoxygenase domain of human Arachidonate 12-lipoxygenase, 12S-type. To be Published, |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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