3D3L

The 2.6 A crystal structure of the lipoxygenase domain of human arachidonate 12-lipoxygenase, 12S-type

3D3L の概要

• エントリーDOI: 10.2210/pdb3d3l/pdb
• 分子名称: Arachidonate 12-lipoxygenase, 12S-type, FE (III) ION (3 entities in total)
• 機能のキーワード: alox12, iron-binding protein, arachidonate 12-lipoxygenase, 12-lox, platelet-type lipoxygenase 12, oxygenase, arachidonate, structural genomics, structural genomics consortium, sgc, cytoplasm, dioxygenase, leukotriene biosynthesis, metal-binding, oxidoreductase, polymorphism
• 由来する生物種: Homo sapiens
• 細胞内の位置: Cytoplasm: P18054
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 122431.95

構造登録者

Tresaugues, L.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Olesen, K.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Welin, M.,Weigelt, J.,Wikstrom, M.,Nordlund, P.,Structural Genomics Consortium (SGC) (登録日: 2008-05-12, 公開日: 2008-09-09, 最終更新日: 2023-08-30)

• 主引用文献: Tresaugues, L.,Moche, M.,Arrowsmith, C.H.,Berglund, H.,Busam, R.D.,Collins, R.,Dahlgren, L.G.,Edwards, A.M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Herman, M.D.,Johansson, A.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nilsson, M.E.,Nyman, T.,Olesen, K.,Persson, C.,Sagemark, J.,Schueler, H.,Svensson, L.,Thorsell, A.G.,Van Den Berg, S.,Welin, M.,Weigelt, J.,Wikstrom, M.,Nordlund, P.; Crystal structure of the lipoxygenase domain of human Arachidonate 12-lipoxygenase, 12S-type.; To be Published,

実験手法

X-RAY DIFFRACTION (2.6 Å)