3D27
E. coli methionine aminopeptidase with Fe inhibitor W29
Summary for 3D27
Entry DOI | 10.2210/pdb3d27/pdb |
Related | 1XNZ |
Descriptor | Methionine aminopeptidase, MANGANESE (II) ION, 4-(3-ethylthiophen-2-yl)benzene-1,2-diol, ... (4 entities in total) |
Functional Keywords | dinuclear, manganese, iron, hydrolase, peptidase, enzyme-inhibitor complex, metalloenzyme, aminopeptidase, cobalt, metal-binding, protease |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 29385.58 |
Authors | |
Primary citation | Wang, W.L.,Chai, S.C.,Huang, M.,He, H.Z.,Hurley, T.D.,Ye, Q.Z. Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity. J.Med.Chem., 51:6110-6120, 2008 Cited by PubMed: 18785729DOI: 10.1021/jm8005788 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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