3D1M
Crystal Structure of Sonic Hedgehog Bound to the third FNIII domain of CDO
Summary for 3D1M
Entry DOI | 10.2210/pdb3d1m/pdb |
Descriptor | Sonic hedgehog protein, Cell adhesion molecule, ZINC ION, ... (5 entities in total) |
Functional Keywords | fibronectin protein-protein complex, autocatalytic cleavage, developmental protein, glycoprotein, hydrolase, lipoprotein, membrane, palmitate, protease, secreted, immunoglobulin domain, transmembrane, signaling protein - cell adhesion complex, signaling protein / cell adhesion |
Biological source | Mus musculus (Mouse) More |
Cellular location | Sonic hedgehog protein C-product: Secreted, extracellular space . Sonic hedgehog protein N-product: Cell membrane ; Lipid-anchor : Q62226 Cell membrane ; Single-pass membrane protein : Q4KMG0 |
Total number of polymer chains | 4 |
Total formula weight | 61673.55 |
Authors | McLellan, J.S.,Leahy, D.J. (deposition date: 2008-05-06, release date: 2008-09-23, Last modification date: 2024-02-21) |
Primary citation | McLellan, J.S.,Zheng, X.,Hauk, G.,Ghirlando, R.,Beachy, P.A.,Leahy, D.J. The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature, 455:979-983, 2008 Cited by PubMed: 18794898DOI: 10.1038/nature07358 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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