3CV5

GOLGI MANNOSIDASE II D204A catalytic nucleophile mutant complex with 3alpha,6alpha-mannopentaose

3CV5 の概要

• エントリーDOI: 10.2210/pdb3cv5/pdb
• 関連するPDBエントリー: 1HTY 1HWW 1HXK 1PS2 1QWN 1QWU 1QX1 1R33 1R34 2ALW 2F7O 2F7P 2F7Q 2F7R 3BUB 3BUD 3BUI 3BUP 3BUQ 3BVT 3BVU 3BVV 3BVW 3BVX
• 分子名称: Alpha-mannosidase 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: family 38 glycosyl hydrolase, glycosidase, golgi apparatus, membrane, metal-binding, signal-anchor, transmembrane, hydrolase
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 120891.11

構造登録者

Shah, N.,Kuntz, D.A.,Rose, D.R. (登録日: 2008-04-17, 公開日: 2008-06-24, 最終更新日: 2023-08-30)

• 主引用文献: Shah, N.,Kuntz, D.A.,Rose, D.R.; Golgi alpha-mannosidase II cleaves two sugars sequentially in the same catalytic site.; Proc.Natl.Acad.Sci.Usa, 105:9570-9575, 2008; PubMed: 18599462; DOI: 10.1073/pnas.0802206105

実験手法

X-RAY DIFFRACTION (1.6 Å)