3CTB
Tethered PXR-LBD/SRC-1p apoprotein
Summary for 3CTB
Entry DOI | 10.2210/pdb3ctb/pdb |
Related | 1ILG 1ILH 1NRL 3CTC |
Descriptor | Pregnane X receptor, Linker, Steroid receptor coactivator 1 (2 entities in total) |
Functional Keywords | pxr, src-1, tethered, engineered, drug-drug interactions, dna-binding, metal-binding, nucleus, receptor, transcription regulation, zinc-finger, transcription, transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q15788 |
Total number of polymer chains | 2 |
Total formula weight | 78368.07 |
Authors | Lesburg, C.A. (deposition date: 2008-04-11, release date: 2008-12-02, Last modification date: 2023-08-30) |
Primary citation | Wang, W.,Prosise, W.W.,Chen, J.,Taremi, S.S.,Le, H.V.,Madison, V.,Cui, X.,Thomas, A.,Cheng, K.C.,Lesburg, C.A. Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability Protein Eng.Des.Sel., 21:425-433, 2008 Cited by PubMed: 18456871DOI: 10.1093/protein/gzn017 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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